nervous system disease: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3100 |
4. Check minimum number of eventsNone |
3100 |
5. Include endpointsNone |
3100 |
6. Filter based on genotype QC (FinnGen only) |
3100 |
Control definitions (FinnGen only)
- Control exclude
- G6_OTHNEU
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G90-G99
- Name in latin
- Morbositates systematis nervosi post interventiones non alibi classificatae
Similar endpoints
↥List of similar endpoints to
Postprocedural disorders of nervous system
based on the number of shared cases.
Similar with more cases:
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 17984 | 12561 | 5331 |
Only index persons | 17409 | 12324 | 5085 |
Unadjusted period prevalence (%) | |||
Whole population | 0.30 | 0.36 | 0.15 |
Only index persons | 0.38 | 0.45 | 0.19 |
Median age at first event (years) | |||
Whole population | 34.51 | 34.74 | 33.96 |
Only index persons | 34.38 | 34.68 | 33.66 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 3100 | 2403 | 697 |
Unadjusted period prevalence (%) | 0.70 | 0.82 | 0.31 |
Median age at first event (years) | 36.92 | 36.10 | 39.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2803
- Matched controls
- 28029
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint G6_POSTOPNEURO and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
G6_POSTOPNEURO | 1.074 [0.92, 1.25] | 0.355 |
Birth year | 0.993 [0.98, 1.0] | 0.098 |
During the follow-up period (1.1.1998 — 31.12.2019), 273 out of 10559 females with G6_POSTOPNEURO died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
G6_POSTOPNEURO | 1.037 [0.9, 1.2] | 0.615 |
Birth year | 0.99 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 240 out of 4412 males with G6_POSTOPNEURO died.
Mortality risk
Mortality risk for people of age
years, who have G6_POSTOPNEURO.N-year risk | Females | Males |
---|---|---|
1 | 0.117% | 0.219% |
5 | 0.627% | 1.243% |
10 | 1.585% | 3.256% |
15 | 2.824% | 6.215% |
20 | 4.87% | 10.678% |
Relationships between endpoints
↥Index endpoint: G6_POSTOPNEURO – Postprocedural disorders of nervous system
GWS hits: 1